{"id":1261,"date":"2025-11-21T06:33:33","date_gmt":"2025-11-21T06:33:33","guid":{"rendered":"https:\/\/snips.nutrifytoday.com\/blog\/?p=1261"},"modified":"2025-11-21T06:33:33","modified_gmt":"2025-11-21T06:33:33","slug":"tocotrienols-in-enhancing-genomic-stability-antioxidant-defense-and-telomerase-activity-in-older-adults","status":"publish","type":"post","link":"https:\/\/snips.nutrifytoday.com\/blog\/tocotrienols-in-enhancing-genomic-stability-antioxidant-defense-and-telomerase-activity-in-older-adults\/","title":{"rendered":"Tocotrienols in Enhancing Genomic Stability, Antioxidant Defense and Telomerase Activity in Older Adults"},"content":{"rendered":"\n<p>This double-blind, parallel-group randomized controlled trial examined the effects of a tocotrienol-enriched drink on markers of aging, oxidative stress, genomic integrity, and psychological well-being in 67 community-dwelling older adults (mean age \u2248 60.5 years) over six months. Participants were divided into two groups, with assessments conducted at baseline, mid-point, and study end. Compared to placebo, the tocotrienol-supplemented group demonstrated significantly greater improvements in psychological quality of life (QOL\u2011Psychological, p = 0.014), as well as favorable trends across key biomarkers: reduced pro-inflammatory cytokine TNF\u2011\u03b1 (p = 0.04), enhanced antioxidant enzyme activities including total superoxide dismutase (T\u2011SOD, p = 0.04) and catalase (p = 0.02), and elevated telomerase levels (p = 0.02), indicative of improved genomic stability. Daily consumption of a tocotrienol-enriched functional beverage over six months appears to bolster antioxidant defense systems, mitigate inflammation, support DNA and telomere integrity, and enhance psychological well-being among older adults, suggesting promising avenues for nutritional strategies aimed at healthy aging.<\/p>\n\n\n\n<p>Source: <a href=\"https:\/\/www.mdpi.com\/2072-6643\/17\/13\/2179\">https:\/\/www.mdpi.com\/2072-6643\/17\/13\/2179<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>This double-blind, parallel-group randomized controlled trial examined the effects of a tocotrienol-enriched drink on markers of aging, oxidative stress, genomic integrity, and psychological well-being in 67 community-dwelling older adults (mean age \u2248 60.5 years) over six months. Participants were divided into two groups, with assessments conducted at baseline, mid-point, and study end. Compared to placebo, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1261","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/posts\/1261","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/comments?post=1261"}],"version-history":[{"count":1,"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/posts\/1261\/revisions"}],"predecessor-version":[{"id":1262,"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/posts\/1261\/revisions\/1262"}],"wp:attachment":[{"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/media?parent=1261"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/categories?post=1261"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/tags?post=1261"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}