{"id":1682,"date":"2026-04-10T10:04:45","date_gmt":"2026-04-10T10:04:45","guid":{"rendered":"https:\/\/snips.nutrifytoday.com\/blog\/?p=1682"},"modified":"2026-04-10T10:04:45","modified_gmt":"2026-04-10T10:04:45","slug":"identification-and-antidiabetic-activity-of-peptides-in-protein-morus-alba-leaf-proteolytic-hydrolysates-a-novel-functional-food-ingredient-for-ameliorating-type-2-diabetes-mellitus","status":"publish","type":"post","link":"https:\/\/snips.nutrifytoday.com\/blog\/identification-and-antidiabetic-activity-of-peptides-in-protein-morus-alba-leaf-proteolytic-hydrolysates-a-novel-functional-food-ingredient-for-ameliorating-type-2-diabetes-mellitus\/","title":{"rendered":"Identification and antidiabetic activity of peptides in protein Morus alba leaf proteolytic hydrolysates: A novel functional food ingredient for ameliorating type 2 diabetes mellitus"},"content":{"rendered":"\n<p>Mulberry leaf protein\u2013derived bioactive peptides exert antidiabetic effects primarily by modulating key glucose-metabolic pathways and inhibiting carbohydrate-digesting enzymes. The identified peptides demonstrated strong \u03b1-glucosidase inhibitory activity, thereby delaying intestinal carbohydrate hydrolysis and reducing postprandial glucose absorption. Additionally, the peptides improved insulin sensitivity and glucose uptake, likely through activation of insulin-signaling pathways such as PI3K\/Akt, leading to enhanced peripheral glucose utilization. Collectively, these mechanisms attenuate hyperglycemia and support metabolic homeostasis, highlighting mulberry leaf peptides as functional agents for glycemic regulation.<\/p>\n\n\n\n<p>Source : <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S2212429225003153\">https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S2212429225003153<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mulberry leaf protein\u2013derived bioactive peptides exert antidiabetic effects primarily by modulating key glucose-metabolic pathways and inhibiting carbohydrate-digesting enzymes. The identified peptides demonstrated strong \u03b1-glucosidase inhibitory activity, thereby delaying intestinal carbohydrate hydrolysis and reducing postprandial glucose absorption. Additionally, the peptides improved insulin sensitivity and glucose uptake, likely through activation of insulin-signaling pathways such as PI3K\/Akt, leading [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1682","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/posts\/1682","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/comments?post=1682"}],"version-history":[{"count":1,"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/posts\/1682\/revisions"}],"predecessor-version":[{"id":1683,"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/posts\/1682\/revisions\/1683"}],"wp:attachment":[{"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/media?parent=1682"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/categories?post=1682"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/snips.nutrifytoday.com\/blog\/wp-json\/wp\/v2\/tags?post=1682"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}