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A 12-week randomized trial explored how palmitoylethanolamide (PEA) affects the gut microbiome and health markers in overweight adults (n=58, BMI 30–40). Participants received either PEA (n=36) or placebo (n=22). PEA supplementation significantly lowered serum triglycerides and IL-2 levels. Gut microbiota composition, richness, and diversity showed no major group differences, but pathway analysis revealed targeted effects:… Read More

The study explores the therapeutic potential of Clitoria ternatea L. (Butterfly Pea) flower extract in managing endometrial pain. Phytochemical screening revealed alkaloids, flavonoids, glycosides, tannins, and steroids, and both in vitro and in vivo experiments showed strong anti-inflammatory and analgesic effects, with significant inhibition of heat-induced hemolysis, carrageenan-induced edema, and acetic acid-induced writhing in mice.… Read More

A randomized, double-blind clinical study compared the effects of a plant-based dietary supplement (PB-Blend, 50 mg) with Vitamin C (1000 mg) in 28 individuals recovering from moderate COVID-19 infection. PB-Blend significantly reduced oxidative stress by inhibiting mitochondrial ROS (−56%), iNOS (−60%), and NOX2-derived ROS (−49%), while Vitamin C only reduced NOX2 activity (−45%). Unlike Vitamin… Read More

Labisia pumila var. alata (LP), long used in traditional women’s health remedies, is now gaining scientific validation for its oestrogenic properties. Research shows that LP contains plant-based phytoestrogens capable of binding to estrogen receptors (ERα and ERβ), mimicking the body’s natural estrogen activity. This is especially relevant during menopause, when declining estrogen levels contribute to… Read More

A crossover trial in 21 college students tested whether paprika-derived xanthophylls (PXs), known antioxidants, enhance physical and mental performance. Compared to control, PX intake lowered heart rate and improved exercise efficiency in both incremental and constant load tests. While group-level differences in cognitive tests weren’t significant, PX users showed within-group improvements in executive function (Trail… Read More