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Aging often disrupts the gut microbiome, but does a daily probiotic help? In a 24-week study of 98 healthy adults aged 75+, researchers tested HOWARU® Restore (a multi-strain probiotic with 10^10 CFU) against a placebo. Participants reported less flatulence and GI discomfort in the probiotic group. Gut bacteria stayed remarkably stable core species from families… Read More
Mycosporine-like amino acids (MAAs) are low-molecular-weight, water-soluble secondary metabolites that provide cellular photoprotection by strongly absorbing UV radiation (310–360 nm) through their cyclohexenone/cyclohexenimine chromophore, thereby preventing UV-induced DNA damage and photooxidative stress. Mechanistically, MAAs dissipate absorbed UV energy as harmless heat and act as potent antioxidants by scavenging reactive oxygen species, stabilizing cellular macromolecules, and… Read More
Pyromeconic acid enriched water extract of Erigeron annuus has been evaluated for its potential as a topical cosmetic ingredient targeting itch relief and skin inflammation. Using human mast cells (HMC-1) and keratinocytes (HaCaT), the extract and its key active compound pyromeconic acid significantly reduced histamine release, a primary trigger of itching, and suppressed pro-inflammatory cytokines… Read More
A randomised controlled trial has demonstrated that replacing sucrose with isomaltulose in caffeinated stimulant beverages significantly attenuates postprandial glycaemic and insulinaemic responses while preserving the cognitive benefits typically associated with energy drink consumption. Conducted across 30 healthy adults aged 21-44, the study measured plasma glucose and insulin at 30 minutes post-ingestion and assessed neurocognitive function… Read More
In a 60-day randomized trial, a combined anthocyanin (riceberry) and prebiotic fiber supplement improved fasting glucose, HbA1c, LDL cholesterol, and kidney function in type 2 diabetes patients compared to placebo. No major effects on inflammation or oxidative stress were seen. The supplement was safe and may serve as supportive therapy. Source : https://pubmed.ncbi.nlm.nih.gov/40218856/ Read More