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Akkermansia Benefits Depend on Baseline Gut Levels
In a 12-week trial in overweight/obese type 2 diabetes patients, Akkermansia supplementation showed metabolic benefits only in those with low baseline gut levels. These participants had reduced body weight, fat mass, and HbA1c. No benefit was seen in those with already high baseline levels. Effects depend on initial gut microbiota status. Source : https://pubmed.ncbi.nlm.nih.gov/39879980/ Read More
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Ascophyllum nodosum extract modulates stem cell and immunecell surveillance in an acute placebo-controlled cross-over trial:Implications for healthy aging
A single serving of the brown seaweed extract PolySea (Ascophyllum nodosum) rapidly modulated immune and regenerative functions in healthy adults, elevating pro-inflammatory cytokines (IFN-γ, IL-6) alongside anti-inflammatory IL-1RA within 1 hour. Transient increases in monocytes and non-NK non-T cells were observed, coupled with selective mobilization of endothelial stem cells and relocation of pluripotent progenitors into… Read More
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Arginine Plus Fish Oil May Improve Muscle Strength and Gait Speed in Sarcopenia
Sarcopenia is an age-related syndrome marked by progressive loss of skeletal muscle mass and function, which contributes to frailty and other adverse health outcomes in older adults. Although arginine and fish oil supplementation individually show potential benefits for muscle preservation, their combined effect has not been well studied. This 12-week randomized clinical trial (December 2023-October… Read More
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Apple Cider Vinegar: A Natural Boost for Weight Loss and Metabolic Health?
Obesity is a global epidemic, and people are turning to simple kitchen staples like apple cider vinegar (ACV) for help. This study explored whether ACV could aid weight loss and improve blood markers in overweight Lebanese adults.In a 12-week trial, 120 participants were split into groups taking 5, 10, or 15 mL of ACV daily,… Read More
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Cardioprotective Potential of Zanthoxylum nitidum Bioactive Compounds
This study evaluated four bioactive compounds from Zanthoxylum nitidum – nitidine chloride, chelerythrine chloride, magnoflorine chloride, and hesperidin to understand their effects on cardiovascular inflammation and myocardial cellular activity. Through integrated analyses the compounds were shown to interact with key cardiovascular targets, particularly prostaglandin-endoperoxide synthase 2 (PTGS2), and influence myocardial ion channels such as IK1… Read More