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Chronic cerebral hypoperfusion (CCH) causes cognitive impairment through BBB disruption, neuroinflammation, mitochondrial dysfunction, neuronal injury, and synaptic impairment, with gut microbiota dysbiosis potentially worsening these effects. Reduced microbiota-derived short-chain fatty acids (SCFAs) may contribute to neurological damage, while SCFAs may protect the brain by regulating neuroinflammation, BBB integrity, mitochondrial function, apoptosis, and synaptic plasticity. Thus, Read More

Researchers have developed an instant plant-based milk from a potato–coconut–peanut blend, fortified with beetroot and turmeric to boost natural bioactives. The formulation aims to offer balanced nutrition alongside antioxidant and enzyme-modulating properties.The three-ingredient blend showed the strongest antioxidant activity and the most favorable sensory ratings among tested samples. It also demonstrated inhibitory effects against enzymes Read More

The clinical study assessed 500 mg/day of bitter hop extract (BHE) in adults with overweight or obesity following diet and exercise advice. BHE, rich in hop bitter acids, was designed to stimulate gut bitter taste receptors and promote the release of appetite-regulating hormones such as GLP-1, CCK, and PYY. Compared with placebo, BHE produced greater Read More

A new Australian clinical study suggests that oleoylethanolamide (OEA) supplementation may stimulate the body’s natural production of GLP-1, opening a potential nutritional approach to appetite and metabolic health. In a single-blind, placebo-controlled crossover study involving 43 overweight and obese adults, a 300 mg dose of OEA increased serum GLP-1 levels within just 15 minutes, with Read More

Super Joints Tablets combine glucosamine, Ashwagandha, Boswellia, curcumin, rosehip, fenugreek, Rasna, and piperine to support cartilage health, mobility, and inflammation management.Their multi-target action may help reduce joint discomfort, stiffness, and oxidative stress associated with osteoarthritis and age-related joint decline. Further clinical studies are needed to confirm their long-term benefits. Source : https://jddtonline.info/index.php/jddt/article/view/7509 Read More