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The study develops a topical formulation containing alginate microspheres loaded with the probiotic strain Lactobacillus casei ATCC 393 and evaluates how it interacts with the skin environment in vitro. The probiotic showed strong activity against Staphylococcus aureus, a common skin pathogen, while remaining compatible with beneficial Staphylococcus epidermidis. The microsphere system was non toxic to… Read More

A 4-week randomized, double-blind, placebo-controlled clinical trial found that AG1® supplementation positively influenced the gut microbiome of healthy adults. AG1® increased beneficial probiotic bacteria such as Lactobacillus acidophilus and Bifidobacterium bifidum, enhanced key functional pathways, and reduced potentially undesirable microbial species. Participants experienced no negative effects on stool consistency, bowel frequency, digestive comfort, or clinical… Read More

S-Equol is a unique gut-derived metabolite formed exclusively by intestinal bacteria from the soy isoflavone daidzein. Unlike its mirror image R-equol, only S-equol shows strong biological activity, exhibiting a remarkably high affinity for estrogen receptor-β—an important target for supporting hormonal balance, skin health, cognitive wellness, and metabolic resilience. Human studies confirm that S-equol is the… Read More

The study evaluated the postbiotic Probio-Eco for chronic constipation using a randomized, double-blind, placebo-controlled crossover trial in adults and a parallel mouse model. In humans, a 3-week Probio-Eco intervention significantly increased complete spontaneous bowel movements, improved stool consistency, and reduced straining compared to placebo. Multi-omics profiling showed that the postbiotic altered gut microbiota composition and… Read More

A new study published in The Lancet reports that daily supplementation with Niagen, a patented form of nicotinamide riboside (NR), may help improve key symptoms in individuals with long COVID. In this first-of-its-kind clinical trial, participants taking Niagen showed meaningful increases in NAD+ levels—up to 3.1-fold after 5–10 weeks—alongside improvements in fatigue, sleep quality, mood… Read More