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This study tested inulin, a natural prebiotic, in obese children for 6 months. Inulin increased healthy gut bacteria, especially Bifidobacterium and butyrate-producing microbes, and improved overall microbiome diversity more than placebo or diet advice. It also changed important microbial functions linked to better metabolic health. Overall, inulin helped restore gut balance and may support healthier… Read More

The authors report the design, fabrication, and in vivo validation of a miniaturized ingestible microdevice (7 × 2.7 mm) that enables site-specific sampling of luminal microbiota and protein biomarkers in the upper gastrointestinal (GI) tract, overcoming limitations of conventional fecal sampling and invasive techniques. The device integrates an enteric-coated gelatin cap that remains intact in… Read More

Researchers are exploring how nature and nanotechnology can join forces to combat acne-causing bacteria and support wound healing. In this study, scientists used Plectranthus aliciae, a South African plant, along with its key compound rosmarinic acid and the antibiotic tetracycline to create gold nanoparticles. These tiny particles were tested for their stability, antibacterial activity, and… Read More

In modern drug discovery, data is both the greatest asset and the biggest bottleneck. Vast biobanks containing clinical, genomic, and real-world health data promise breakthroughs, yet inconsistent formats, missing values, and poor standardization often slow progress. Just as cluttered storage delays finding what matters, poorly curated data limits the power of advanced tools like artificial… Read More

Menopause-associated estrogen decline accelerates systemic and dermal aging through dysregulated extracellular matrix turnover and increased protein glycation, making circulating biomarkers a useful non-invasive monitoring tool. In this randomized, double-blind, placebo-controlled study, 65 healthy postmenopausal women (45–70 years) received 250 mg/day olive leaf extract (OLE) or placebo for 12 weeks to assess effects on tissue aging… Read More