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Dietary supplementation with a concentrate enriched in milk fat globule membranes (MFGMs) and extracellular vesicles (EVs) promotes the accretion of distinct sphingolipid profiles in aged sedentary rats, including reductions in plasma ceramides associated with elevated cardiovascular risk. Over a 25-week intervention, the MFGM/EV-rich supplement significantly improved lipoprotein particle profiles marked by reduced triglyceride-rich lipoproteins and… Read More
This double-blind, parallel-group randomized controlled trial examined the effects of a tocotrienol-enriched drink on markers of aging, oxidative stress, genomic integrity, and psychological well-being in 67 community-dwelling older adults (mean age ≈ 60.5 years) over six months. Participants were divided into two groups, with assessments conducted at baseline, mid-point, and study end. Compared to placebo,… Read More
A recent study has found that olive leaf polyphenols may subtly influence insulin response after meals, even though they do not significantly impact post-meal blood sugar or lipid levels in the short term. In a randomized crossover trial involving 36 healthy adults, participants consumed either olive leaf tea, biscuits made with olive leaf powder, or… Read More
A sub-study of the large-scale VITAL randomized controlled trial investigated the effects of vitamin D3 and marine omega-3 fatty acids on leukocyte telomere length (LTL), a biomarker of cellular aging. Over four years, vitamin D3 supplementation (2,000 IU/day) significantly slowed telomere attrition compared to placebo, indicating a protective effect against cellular aging. Participants receiving vitamin… Read More
A double-blind, placebo-controlled study in competitive sprint swimmers found that combining multi-strain probiotics (4.5×10¹¹ CFU) and omega-3 fatty acids (1000 mg/day: 500 mg EPA, 180 mg DHA) with Ultra-Short Race Pace Training (USRPT) led to synergistic improvements in performance. Over 8 weeks, the combined group showed the greatest gains reducing 50 m and 100 m… Read More