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Lower urinary tract symptoms (LUTS) are common in aging men and can significantly impact quality of life. In a 12-week randomized pilot study, 30 men with LUTS received either 400 mg/day of Salvia miltiorrhiza extract (SAGX) or 320 mg/day of saw palmetto extract. SAGX produced significantly greater improvements in overall urinary symptoms, particularly storage symptoms… Read More
Daily supplementation with cumin essential oil (CEO), rich in cuminaldehyde, for 12 weeks significantly improved cognitive performance in older adults (65–86 years) compared with placebo. Participants receiving CEO demonstrated notable enhancements in psychomotor speed and reaction time, indicating improved processing speed and cognitive responsiveness. While certain blood biomarkers changed over time, these effects were not… Read More
In a 6-month trial of 225 patients with androgenic alopecia, adding AGA-P (Serenoa repens, pumpkin seed extract, L-cystine, vitamin C) to minoxidil/finasteride improved outcomes versus drug therapy alone. Significant improvement was seen in 36.5% of supplemented patients compared with 25% of controls, suggesting AGA-P enhances hair growth treatment efficacy. Source : https://pubmed.ncbi.nlm.nih.gov/40853071/ Read More
This randomized, double‑blind, placebo‑controlled trial investigated the gut‑healing effects of the isolated hydroxycinnamic acid amide N‑trans caffeoyltyramine (NCT) in adults with diarrhea‑predominant IBS. Over three weeks, oral supplementation significantly improved intestinal barrier integrity, shown by a reduced Lactulose/Mannitol ratio (𝑝 = 0.048), and lowered systemic inflammation through decreased lipopolysaccharide‑binding protein levels (𝑝= 0.018) compared to… Read More
The study evaluates how the bacterial effector protein IpaH2, an E3 ubiquitin ligase produced by Shigella flexneri, influences viral infection mechanisms within host cells. The researchers identified plakophilin-2 (PKP2), a cellular adhesion and signaling protein, as a previously unrecognized host restriction factor that limits the replication of Sindbis virus. Through its ubiquitin ligase activity, IpaH2… Read More