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A randomised controlled trial has demonstrated that replacing sucrose with isomaltulose in caffeinated stimulant beverages significantly attenuates postprandial glycaemic and insulinaemic responses while preserving the cognitive benefits typically associated with energy drink consumption. Conducted across 30 healthy adults aged 21-44, the study measured plasma glucose and insulin at 30 minutes post-ingestion and assessed neurocognitive function… Read More
In a 60-day randomized trial, a combined anthocyanin (riceberry) and prebiotic fiber supplement improved fasting glucose, HbA1c, LDL cholesterol, and kidney function in type 2 diabetes patients compared to placebo. No major effects on inflammation or oxidative stress were seen. The supplement was safe and may serve as supportive therapy. Source : https://pubmed.ncbi.nlm.nih.gov/40218856/ Read More
A population-based cohort study from Southern Italy demonstrates a clear inverse association between Italian-style coffee consumption and the risk of metabolic dysfunction-associated steatotic liver disease (MASLD), with a dose-dependent reduction observed as intake increases. Compared to individuals consuming less than one cup per day, those consuming 1, 2, and 3 cups daily showed progressively lower… Read More
Mulberry leaf protein–derived bioactive peptides exert antidiabetic effects primarily by modulating key glucose-metabolic pathways and inhibiting carbohydrate-digesting enzymes. The identified peptides demonstrated strong α-glucosidase inhibitory activity, thereby delaying intestinal carbohydrate hydrolysis and reducing postprandial glucose absorption. Additionally, the peptides improved insulin sensitivity and glucose uptake, likely through activation of insulin-signaling pathways such as PI3K/Akt, leading… Read More
The study evaluated the root extract of Paeonia lactiflora, standardized for paeoniflorin, for its ability to modulate inflammation and protect tissue integrity in skin keratinocytes and oral gingival fibroblasts under inflammatory conditions. Using lipopolysaccharide (LPS) induced in vitro models along with in silico analysis, the extract reduced the activity of TRPV1 channels and lowered the… Read More