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This paper (Liu et al., 2025) provides a high-level review of the Gut–Brain Axis (GBA) as a target for precision nutraceutical interventions in the management of malnutrition, emphasizing the role of the microbiome as a predictive indicator of metabolic health. Centrally, it highlights how short-chain fatty acids (SCFAs) the primary metabolites of probiotic fermentation (such… Read More
Pycnogenol®, a patented extract from Pinus pinaster Ait. ssp. Atlantica bark, shines in 39 randomized, double-blind, placebo-controlled trials with over 2,000 participants. Supplementation (2 weeks to 6 months) delivers wide-ranging benefits: bolstering cardiovascular and endothelial health, easing chronic venous insufficiency, enhancing cognition, joint and skin elasticity, eye and women’s health, respiratory function, allergy relief, oral… Read More
The study investigated Geranium essential oil (Pelargonium graveolens) and Calendula essential oil (Calendula officinalis) encapsulated in ethanolic lipid vesicles for topical delivery. The vesicular formulation enhanced the stability and skin penetration of volatile bioactive compounds, including citronellol, geraniol, and alpha pinene. By increasing diffusion through the stratum corneum, the vesicles allowed the active compounds to… Read More
A 12-week randomized controlled trial in older adults showed that daily intake of 30 g soy protein preserved muscle mass and improved muscle performance compared with usual diet, alongside beneficial shifts in the gut microbiome. The intervention increased short-chain fatty acid–producing bacteria, reduced taxa linked to poorer muscle outcomes, enriched amino acid metabolism and vitamin… Read More
This network meta-analysis of 79 RCTs (5,501 women) found that chromium, inositol, omega-3, soy isoflavones, curcumin, and carnitine improve different PCOS markers. Chromium benefits hormones and antioxidant status, inositol improves lipids, omega-3 reduces insulin resistance, and soy isoflavones reduce oxidative stress. Supplements showed no major effect on testosterone or inflammatory markers. Source : https://pubmed.ncbi.nlm.nih.gov/40611279/ Read More