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A new study in the Journal of Investigative Dermatology reveals how dietary vitamin C—not topical serums—directly boosts the skin’s internal ascorbate levels and impacts its biological function. While vitamin C is celebrated for collagen support and antioxidant protection, researchers show that oral intake meaningfully raises ascorbate concentrations in both the dermis and epidermis via SVCT… Read More

Spermidine, an essential cellular polyamine that declines with age is increasingly recognized for its impact on longevity, cognitive performance, and cellular resilience. While oral spermidine shows benefits in animal models, much of its activity may originate in the gut, rather than through systemic elevation. To harness this gut-centric mechanism, researchers engineered the probiotic yeast Saccharomyces… Read More

This review analyzed 11 clinical trials with 870 people to see if oral collagen helps knee osteoarthritis. Compared to placebo, collagen significantly reduced knee pain and improved daily function. Overall results showed meaningful and clinically important benefits, suggesting collagen supplements can help relieve symptoms of knee OA. Source : https://pubmed.ncbi.nlm.nih.gov/39212129/ Read More

The study focuses on extracting pectins from the fruit of Passiflora ligularis and evaluating their potential use as a natural moisturizing ingredient in cosmetic formulations. The researchers optimized the extraction process to obtain pectin with good purity and stability, then characterized it using physicochemical and structural analyses. They found that the extracted pectin has strong… Read More

Pycnogenol, a standardized French maritime pine bark extract, demonstrated efficacy in short-term randomized, placebo-controlled ADHD trials, improving hyperactivity, inattentiveness, and visual-motor coordination. Mechanistically, its effects are attributed to nitric oxide–mediated modulation of catecholamine signaling, potent antioxidant activity, normalization of urinary catecholamines, and enhanced cerebral blood flow. Despite minimal side effects, limited sample sizes and study… Read More