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Fish oil is rich in EPA and DHA, but these delicate omega-3 fats are highly prone to oxidation if exposed to air, heat, or poor storage. Oxidation doesn’t just affect taste, it can also reduce the nutritional integrity of the oil. Research shows that 30-45% of retail fish oil products may exceed recommended oxidation limits,… Read More
Could a common amino acid help sharpen the aging mind? A recent 10-week study suggests that β-alanine (BA) supplementation might improve cognitive function and mood in older adults.Researchers followed 100 participants, average age 71, who took either 2.4 grams of β-alanine or a placebo daily. They underwent memory, attention, and mood tests including the Montreal… Read More
This study identifies Siglec-10 as a dominant inhibitory glyco-immune checkpoint on tumor-associated macrophages (TAMs) in pancreatic ductal adenocarcinoma (PDAC) and demonstrates that PDAC cells evade innate and adaptive immunity by exploiting sialylated integrin α3β1 (ITGA3–ITGB1) as a functional ligand for Siglec-10. Mechanistically, α3β1 on PDAC cells is heavily sialylated, enabling high-affinity engagement of Siglec-10 on… Read More
Studies examining folate intake and breast cancer risk present a mixed and often conflicting picture, with some reporting a protective association, others finding no relationship, and a few suggesting a U-shaped effect where both low and high intakes may influence risk differently. This inconsistency likely reflects differences in baseline folate status, dietary versus supplemental sources,… Read More
A newly published clinical trial is set to reshape how the nutraceutical industry approaches NAD⁺ enhancement. In a peer-reviewed, randomized, double-blind, placebo-controlled study in the Journal of Functional Foods, researchers showed that the botanical complex BluNADBooster outperformed the long-standing benchmark NAD⁺ precursor, nicotinamide riboside (NR), across multiple healthy-ageing domains.The study demonstrated that BluNADBooster significantly improved… Read More