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Milk-Derived Nutraceutical Shows Promise in Fighting Age-Related Metabolic Decline
A new animal study suggests that a milk-derived supplement rich in milk fat globule membranes (MFGMs) and extracellular vesicles (EVs) could help combat age-related metabolic dysfunction. Over 25 weeks, aged sedentary rats given the MFGM/EV concentrate — abundant in milk sphingolipids — developed healthier lipid profiles, including reductions in ceramide biomarkers tied to cardiovascular death… Read More
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Milk-Derived Nutraceutical Improves Lipid Metabolism and Heart Health in Aging
Dietary supplementation with a concentrate enriched in milk fat globule membranes (MFGMs) and extracellular vesicles (EVs) promotes the accretion of distinct sphingolipid profiles in aged sedentary rats, including reductions in plasma ceramides associated with elevated cardiovascular risk. Over a 25-week intervention, the MFGM/EV-rich supplement significantly improved lipoprotein particle profiles marked by reduced triglyceride-rich lipoproteins and… Read More
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Tocotrienols in Enhancing Genomic Stability, Antioxidant Defense and Telomerase Activity in Older Adults
This double-blind, parallel-group randomized controlled trial examined the effects of a tocotrienol-enriched drink on markers of aging, oxidative stress, genomic integrity, and psychological well-being in 67 community-dwelling older adults (mean age ≈ 60.5 years) over six months. Participants were divided into two groups, with assessments conducted at baseline, mid-point, and study end. Compared to placebo,… Read More
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Olive Leaf Polyphenols Show Promise in Modulating Post-Meal Insulin Response, Study Finds
A recent study has found that olive leaf polyphenols may subtly influence insulin response after meals, even though they do not significantly impact post-meal blood sugar or lipid levels in the short term. In a randomized crossover trial involving 36 healthy adults, participants consumed either olive leaf tea, biscuits made with olive leaf powder, or… Read More
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Vitamin D3 Supplementation Slows Cellular Aging: Evidence from the VITAL Telomere Study
A sub-study of the large-scale VITAL randomized controlled trial investigated the effects of vitamin D3 and marine omega-3 fatty acids on leukocyte telomere length (LTL), a biomarker of cellular aging. Over four years, vitamin D3 supplementation (2,000 IU/day) significantly slowed telomere attrition compared to placebo, indicating a protective effect against cellular aging. Participants receiving vitamin… Read More