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The study investigated Geranium essential oil (Pelargonium graveolens) and Calendula essential oil (Calendula officinalis) encapsulated in ethanolic lipid vesicles for topical delivery. The vesicular formulation enhanced the stability and skin penetration of volatile bioactive compounds, including citronellol, geraniol, and alpha pinene. By increasing diffusion through the stratum corneum, the vesicles allowed the active compounds to… Read More

A 12-week randomized controlled trial in older adults showed that daily intake of 30 g soy protein preserved muscle mass and improved muscle performance compared with usual diet, alongside beneficial shifts in the gut microbiome. The intervention increased short-chain fatty acid–producing bacteria, reduced taxa linked to poorer muscle outcomes, enriched amino acid metabolism and vitamin… Read More

This network meta-analysis of 79 RCTs (5,501 women) found that chromium, inositol, omega-3, soy isoflavones, curcumin, and carnitine improve different PCOS markers. Chromium benefits hormones and antioxidant status, inositol improves lipids, omega-3 reduces insulin resistance, and soy isoflavones reduce oxidative stress. Supplements showed no major effect on testosterone or inflammatory markers. Source : https://pubmed.ncbi.nlm.nih.gov/40611279/ Read More

Dileucine, a di-peptide composed of two leucine molecules (L-leucyl-L-leucine), is emerging as a next-generation amino acid ingredient for muscle health, particularly in the context of sarcopenia, because it is absorbed via the PEPT1 peptide transporter rather than standard amino-acid pathways, enabling faster and more efficient delivery of leucine to muscle tissue; this is especially relevant… Read More

In a randomized, placebo-controlled trial of 1228 hemodialysis patients, daily fish oil supplementation (4 g n-3 PUFA: 1.6 g EPA, 0.8 g DHA) significantly reduced serious cardiovascular events compared with placebo over 3.5 years (HR 0.57; 95% CI, 0.47–0.70). Benefits extended to cardiac death, myocardial infarction, stroke, amputation, and all-cause mortality, with adherence and adverse… Read More