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  • Modulating Energy and Redox Homeostasis: A Review of Creatine, L-Carnitine, Melatonin, and Resveratrol in Neurodegenerative Diseases and Organic Acidemias

    This review analyzes the contribution of energy metabolism and redox imbalance to neurological and neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and cerebral organic acidurias, and evaluates selected nutraceuticals as neuroprotective adjuvants. It focuses on creatine, acetyl-L-carnitine, melatonin, and resveratrol, emphasizing their roles in regulating mitochondrial bioenergetics, ATP buffering, oxidative stress, and apoptosis. Creatine supports… Read More


  • Microneedle based delivery of Kinsenoside for Chronic Diabetic Wound Management

    This study describes the development of a multifunctional microneedle platform designed to overcome the poor healing seen in diabetic wounds, which is largely driven by chronic inflammation, oxidative stress, and infection. The researchers created a hydrogel based microneedle patch (HAQA-MN) loaded with kinsenoside that was coated with a macrophage membrane (M-KD), allowing the treatment to… Read More


  • Natural Mouthwashes and Toothpastes: Do Herbs Really Fight Plaque and Gingivitis Better?

    Countless studies and reviews have tested herbal versus standard oral care products for tackling plaque buildup and gum inflammation (gingivitis). But results often clash, leaving people confused. This umbrella review pulls together data from existing systematic reviews to clarify how herbal mouthrinses and toothpastes stack up against conventional options or placebos.We scoured six major databases… Read More


  • Aronia Anthocyanins and Executive Function

    A six-week randomized, double-blind, placebo-controlled crossover study in older adults with overweight or obesity found that daily supplementation with 40 mg anthocyanins from Aronia melanocarpa extract improved executive function without broadly altering vascular markers. While cerebral blood flow in predefined brain regions remained unchanged, a localized decrease was observed in the right insular cortex, the… Read More


  • Innovation Outpacing Regulation: A Compliance Wake-Up Call for the Nutra Industry

    As novel supplement delivery formats such as gummies, bars, RTD shots, pouches, strips, and liquid sachets proliferate, the nutraceutical industry is entering a regulatory gray zone where innovation is increasingly outpacing compliance. Legal experts caution that many of these formats risk falling outside the legal definition of a dietary supplement under DSHEA, particularly when products… Read More


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