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Mango leaf extract, rich in the polyphenol mangiferin, is widely touted for its potential brain health benefits, but not all studies agree on its effectiveness. In a recent gold-standard trial, healthy adults given a single 300 mg dose of mango leaf extract saw no improvements in cognitive performance or mood; in fact, they made more… Read More

A new analysis of U.S. children and adolescents finds that higher blood levels of carotenoids are linked to lower obesity risk. Using NHANES 2017–2018 data from 1,329 participants, researchers reported that all carotenoids studied except lycopene were associated with lower BMI and reduced odds of obesity. β-carotene showed the strongest effect, while the combined carotenoid… Read More

Astragalus polysaccharides (APS), a major bioactive component of Astragalus, exert promising anti-obesity effects through multiple mechanisms involving various organs and pathways. APS helps alleviate obesity-related inflammation by suppressing the TLR4/NF-κB signaling pathway and lowering pro-inflammatory cytokines, while also improving insulin sensitivity and regulating glucose metabolism. It reduces hepatic fat accumulation, thereby protecting against non-alcoholic fatty… Read More

A crossover trial in 21 college students found that short-term supplementation with paprika xanthophylls (PXs) improved exercise efficiency and reduced heart rate during both incremental and constant load tests. While no significant between-group differences were seen in cognition overall, PX intake enhanced performance in the Trail Making Test-B and Stroop interference tasks. These findings suggest… Read More

This double-blind, randomized, placebo-controlled trial investigated the effects of a combined anthocyanin (riceberry rice) and prebiotic soluble fiber (rice bran, Jerusalem artichoke) supplement in 60 patients with type 2 diabetes mellitus (T2DM). Participants received either the supplement (2.8 g/day) or maltodextrin placebo for 60 days. Compared with placebo, the supplement group showed significant improvements in… Read More