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Astragalus polysaccharides (APS), a major bioactive component of Astragalus, exert promising anti-obesity effects through multiple mechanisms involving various organs and pathways. APS helps alleviate obesity-related inflammation by suppressing the TLR4/NF-κB signaling pathway and lowering pro-inflammatory cytokines, while also improving insulin sensitivity and regulating glucose metabolism. It reduces hepatic fat accumulation, thereby protecting against non-alcoholic fatty… Read More

A crossover trial in 21 college students found that short-term supplementation with paprika xanthophylls (PXs) improved exercise efficiency and reduced heart rate during both incremental and constant load tests. While no significant between-group differences were seen in cognition overall, PX intake enhanced performance in the Trail Making Test-B and Stroop interference tasks. These findings suggest… Read More

This double-blind, randomized, placebo-controlled trial investigated the effects of a combined anthocyanin (riceberry rice) and prebiotic soluble fiber (rice bran, Jerusalem artichoke) supplement in 60 patients with type 2 diabetes mellitus (T2DM). Participants received either the supplement (2.8 g/day) or maltodextrin placebo for 60 days. Compared with placebo, the supplement group showed significant improvements in… Read More

Low-glycemic carbohydrate isomaltulose (ISO) supports incretin release and improves postprandial control via the second meal effect (SME), relevant for metabolic syndrome (MetS). In a randomized crossover trial, 15 MetS subjects received ISO or sucrose (SUC) preloads 1 h or 3 h before a test meal. ISO blunted glucose rise (ΔG/Δt: 0.28 vs. 0.53 mmol/L/min, p<0.01),… Read More

The recent study on a compound called Dehydroeburicoic Acid (DEA), a triterpenoid found in the fungus Antrodia cinnamomea. It identifies DEA as a potential therapeutic agent for Alcoholic Liver Disease (ALD). The research reveals that DEA acts as a dual inhibitor,uniquely targeting two key cellular pathways: the Keap1-Nrf2 protein-protein interaction (PPI) and glycogen synthase kinase… Read More